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GlossaryTrichilemmal Cysts

non-cancerous, keratin-filled lumps typically found on the scalp

Trichilemmal cysts, also known as pilar cysts, are non-cancerous, fluid-filled lumps that typically develop on the scalp. They originate from the outer root sheath of hair follicles and are filled with keratin, a protein found in hair, skin, and nails. These cysts are usually firm, smooth, and can sometimes be hereditary.

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research Proliferating Trichilemmal Cyst With Histological Malignant Transformation: Identification of Hair Sheath Keratins in the Tumor

3 citations , January 1989 in “The Nishinihon Journal of Dermatology”

A hair cyst can become cancerous, showing specific keratins from the hair sheath.

research Malignant Appearance of Trichilemmal Cyst: A Case Report With Review of the Literature

November 2023 in “International surgery journal”

A man's neck lump was a trichilemmal cyst, not cancer, and should be fully removed due to rare risk of becoming malignant.

research Immunoperoxidase Anti-Keratin Staining of Epidermal and Pilar Cysts

10 citations , July 1984 in “British Journal of Dermatology”

Epidermal cysts come from the skin, while pilar cysts come from hair follicles.

research Baker's Dozen on the Scalp: An Interesting Case of Multiple Trichilemmal Cysts

5 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

A woman had 13 non-cancerous cysts on her scalp successfully removed in one surgery.

research Trichilemmal Cyst of the Eyelid: An Unusual Presentation in Pediatric Age Group

January 2026 in “Indian Journal of Ophthalmology - Case Reports”

Trichilemmal cysts can appear on children's eyelids and may be mistaken for other conditions.

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