49 citations
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July 2007 in “Ophthalmic Plastic and Reconstructive Surgery” This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.
June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
97 citations
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May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
In this study, pilomatricoma, a benign skin tumor from hair follicle matrix cells, is highlighted as an important consideration when diagnosing painless, firm subcutaneous nodules, with accurate diagnosis relying on histopathological examination.
6 citations
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November 2024 in “Medicine International” In this systematic review, researchers reported that post-COVID-19 syndrome can lead to various dermatological symptoms, including skin rash, alopecia, pruritus, and dermatitis, with a notable prevalence of autoimmune-related skin changes, especially among females and those with severe COVID-19 history.