research Controlling MTORC1 Activity as a Novel Therapeutic Strategy for Managing Human Hair Growth and Pigmentation July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
research Increased Cathepsin B Expression in Cultured Tuberous Sclerosis Skin Tumor Cells and Patient Tumor Tissues April 2012 Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.
research Anticancer Effects of Metformin on Neuroendocrine Tumor Cells In Vitro 22 citations, July 2014 in “Hormones” Metformin may help treat neuroendocrine tumors.