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GlossaryTopiramate (Topamax)

medication used to treat epilepsy and prevent migraines

Topiramate, also known by brand names such as Topamax, is a medication primarily used to treat epilepsy and prevent migraines. It works by stabilizing electrical activity in the brain and has additional off-label uses, including for weight loss and mood stabilization.

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research Topiramate vs Divalproex Sodium in the Preventive Treatment of Migraine: A Prospective Real-World Study

19 citations, April 2011 in “Headache The Journal of Head and Face Pain”

Both topiramate and divalproex sodium effectively reduce migraine frequency and are generally well-tolerated.

research Acneiform Rash Caused by an Unlikely Drug: Topiramate

5 citations, July 2017 in “Skin appendage disorders”

A man got a rare rash from the drug topiramate, which went away after he stopped taking it.

research Topiramate-Induced Hair Loss: Case Report

2 citations, January 2002 in “Dermatology + psychosomatics”

Topiramate may cause reversible hair loss.

research Safety and Tolerability of Antiepileptic Drugs in Women with Epilepsy

1 citations, April 2015 in “Russkij žurnal detskoj nevrologii”

Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.

research Where It All Went Right: Secondary Uses of Drugs

1 citations, December 2014

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

research Reporting on Adverse Clinical Events

October 2008 in “Clin-alert”

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.