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Sebocytes play a key role in controlling androgen levels in human skin.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.