2 citations
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January 2023 in “Ceramics International” In this study, the Cu-doped bioglass composite dressings showed promising results for wound healing and hair follicle regeneration in vitro, with enhanced fibroblast proliferation and vascular growth.
8 citations
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January 2020 in “Biomaterials Science” In this study, small molecule-loaded silk fibroin nanofiber scaffolds with chitosan achieved sustained release of GSK-3 inhibitor SB216763, leading to enhanced wound healing and hair follicle neogenesis in skin regeneration efforts.
308 citations
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September 2010 in “Nucleic acids research” This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.
91 citations
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December 2010 in “Stem Cells” This study found that Wnt signaling regulates the symmetric division of adult neural stem cells, increasing their numbers during subependymal regeneration, stroke response, and colony formation.
29 citations
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March 2010 in “Journal of Dermatological Science” This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.
1 citations
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April 2016 in “Journal of Investigative Dermatology” This study identified that blocking the PTGDR2 receptor in human hair follicles in vitro and in mice reversed the hair growth inhibition caused by PGD2, suggesting a potential approach for treating alopecia.
July 2026 in “Nature Communications” In this study, researchers used patient-derived organoids to model metastasis in colorectal cancer and discovered that cancer cells temporarily switch to a wound-healing program, orchestrated by reduced EZH2 activity and YAP signaling, before spreading to new organs.
April 2016 in “Journal of Investigative Dermatology” This study found that inhibiting JAK signaling can unexpectedly trigger hair growth in resting-phase mouse skin, implicating JAK-STAT pathways and oncostatin M in maintaining hair follicle stem cell quiescence.
April 2016 in “Journal of Investigative Dermatology” This study suggests that dsRNA may enhance KRT9 expression in palm and sole skin through β-catenin signaling, potentially linking mechanical damage to specific skin features and certain skin conditions.
April 2016 in “Journal of Investigative Dermatology” This study provides a comprehensive platform to explore stem cell interactions regulating hair follicle growth, revealing key signaling pathways in epithelial-mesenchymal interactions using advanced RNA sequencing and transgenic reporters.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
April 2016 in “Journal of Investigative Dermatology” This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” October 2012 in “Sax's Dangerous Properties of Industrial Materials” September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” The document's conclusion cannot be determined because the content is not available.
1 citations
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September 2010 in “European Urology Supplements”
September 2019 in “Journal of Investigative Dermatology” This clinical trial reported that Sandalore® 1% significantly reduced hair shedding and increased hair volume and anagen HFs in women with telogen effluvium compared to placebo, supporting its potential use in hair growth treatments.
9 citations
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May 2014 in “Journal of Cardiovascular Development and Disease” This review discusses the role of Wnt signaling in cardiac development and explores attempts to modulate it for improving heart function after ischemic injury, but reports no new experimental results.
May 2025 in “Antioxidants” This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.
March 2009 in “European Urology Supplements” September 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
The document cannot be summarized as it is not provided or is unclear.
September 2023 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated how subjects perceive the effectiveness of three FDA-cleared photobiomodulation devices for home use in treating androgenetic alopecia, though specific outcomes or comparative effectiveness are not reported in the abstract.
3 citations
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January 2018 in “Research Journal of Pharmacy and Technology” In this animal study, SM-215 treatment in male mice showed increased hair growth and decreased indicators of hair follicle damage and scalp inflammation, suggesting potential benefits for androgenetic alopecia.
December 2025 in “ILDS-DEV” 27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.
7 citations
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May 2011 in “Hair transplant forum international” This report presents no new clinical results; it discusses the application of ACell MatriStem™, a porcine urinary bladder-derived extracellular matrix, in wound healing.
September 2023 in “Hair transplant forum international” This announcement from the American Board of Hair Restoration Surgery details the establishment of two oral examinations for 2024, with the first taking place at the Italian/European Congress in Milan, Italy, in May.