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A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The method increases stem-like cells for better skin regeneration.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Enzymes play crucial roles in metabolism, health, and disease management.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Pilose antler extracts help hair growth by activating hair follicle stem cells.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

New therapies are being developed that target integrin pathways to treat various diseases.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Lower SMAD2/3 activation predicts more severe skin cancer.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.