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Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The Rotterdam Study aims to understand various diseases in older adults.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.