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Dermatological conditions are complex and treatments often have mixed results.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

Improving mitochondrial health may better treat atherosclerosis than antioxidants.

A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Activating Nrf2 can help protect against hearing loss.

An American Bully with a genetic skin condition improved significantly with specific topical treatments.

Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.

A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Reactive oxygen species (ROS) help control plant growth and development.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

IMA may indicate oxidative stress in skin and hair disorders, but more research is needed.

Enzymes called PADIs play a key role in hair growth and loss.

New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.

Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Skin, hair, and nail changes can help detect eating disorders early.