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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Spironolactone may help enlarge a small breast linked to Becker's nevus.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Testosterone is crucial for development, growth, and various body functions in mammals.

Spironolactone might lower the chance of getting rosacea.

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

Excess androgens may cause PCOS, not just be a symptom.

Zinc is essential for plant growth and human health, but many soils lack enough zinc, affecting crops and potentially leading to health problems.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

The glucocorticoid receptor helps protect skin from tumors and other issues.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The circadian clock influences the behavior and regeneration of stem cells in the body.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

New drugs are improving treatment for hormone-related diseases in small pets.