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TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Mice with human skin protein K8 had more skin problems and cancer.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

New drugs are improving treatment for hormone-related diseases in small pets.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Tamoxifen caused hair loss in a 52-year-old woman.