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Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Women with PCOS have lower adiponectin hormone levels and are more likely to have insulin resistance.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

The dietary supplement helped increase hair growth in women with hair loss.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Trichoscopy helps diagnose and assess the severity of Frontal Fibrosing Alopecia.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.