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Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Different types of stem cells and their environments are key to skin repair and maintenance.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Fat cells help recruit healing cells and build skin structure during wound healing.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Turning scar-forming cells into fat cells can reduce scarring.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.