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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

The document explains the genetic causes and characteristics of inherited hair disorders.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Exosomes can help repair and heal tissues, improving health and vitality.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Pannexin 3 is important for bone formation and the development of bone cells.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The shape of fibrous scaffolds can improve how stem cells help heal skin.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Substance from human umbilical cord blood cells promotes hair growth.

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.