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Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Laminin 332 is essential for normal skin cell behavior and structure.

An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

New genetic mutations linked to rare skin disorders were found in three newborns.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

A specific gene mutation causes Olmsted syndrome.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

Inflammation and Demodex mites might contribute to hair loss, and targeting them could help treat it.

The document concludes that accurate diagnosis and understanding the type of hair disorder are crucial for treating hair loss in children.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

The review shows how to properly diagnose and treat the loss of eyebrow and eyelash hair.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.

Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.