19 citations,
March 2022 in “International Journal of Environmental Research and Public Health” Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.
18 citations,
October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
18 citations,
June 2009 in “Journal of Molecular Endocrinology” Finasteride exposure harms tadpole reproduction and hormone balance.
16 citations,
July 2020 in “Psychoneuroendocrinology” People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
13 citations,
October 2006 in “Pediatrics in review” Early puberty is more common in girls and African-American children, possibly due to nutrition, obesity, stress, and environmental factors, and is treated with hormone therapy.
8 citations,
January 1986 in “Journal of hepatology” Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
3 citations,
January 2017 in “Journal of clinical and diagnostic research” Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.
2 citations,
February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
1 citations,
February 2023 in “Drug Design Development and Therapy” Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
December 2023 in “JCEM case reports” A new gene variant causes glucocorticoid resistance in a mother and son.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.
September 2023 in “F&S reports” PCOS may increase the risk of mental health issues like depression and anxiety.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
May 2023 in “Animal Reproduction Update” High levels of cortisol in hair show long-term stress which can lower fertility in animals.
July 2022 in “International journal of medical science and clinical invention” Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.
June 2020 in “Authorea (Authorea)” First-time mothers had higher stress hormone levels in late pregnancy than mothers who had given birth before.
June 2007 in “Endocrinology and Metabolism Clinics of North America” The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.
131 citations,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
January 2018 in “Elsevier eBooks” The document explains how male reproductive hormones work and affect the body.
430 citations,
July 2002 in “Journal of Endocrinology” The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.
43 citations,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
38 citations,
April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
11 citations,
October 2020 in “General and comparative endocrinology” Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
7 citations,
March 2022 in “Journal of the American Academy of Dermatology” Stress can trigger or worsen alopecia areata.
1 citations,
June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
May 2011 in “Journal of The American Academy of Dermatology” Objective assessment is needed to accurately determine medication use and adherence.
26 citations,
July 1995 in “Neurobiology of Aging” Finasteride affects prostate weights and pituitary activity differently with age.
1 citations,
October 2022 in “International journal of endocrinology” Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
October 2012 in “Semina. Ciências Agrárias” A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.
1 citations,
June 2012 in “Springer eBooks” Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.