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Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Special fiber materials boost the healing properties of certain stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Oestrogens are key for bone growth during puberty in both boys and girls.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Humans lost body hair relatively recently in evolution.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Testosterone's muscle-building effects do not require its conversion to DHT.