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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Keratins are important for skin cell health and their problems can cause diseases.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Hair proteins have weak spots in their α-helical segments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.

Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.

Hair straightening can damage hair and pose health risks, including exposure to carcinogens and hair loss.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.

Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.

Avoid chemical and physical damage to protect hair.

Repeated use of protein hair conditioner with heat or gamma irradiation can harm skin and hair health in rats.

Hair straightening changes hair structure and can cause damage if done wrong, but improvements in the methods are expected to continue.

Hair straightening methods have advanced to improve effectiveness and reduce damage, but still rely on heat and chemicals.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Hair care products clean, protect, style, color, and change hair structure.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Juglone from walnut extracts may help repair damaged hair.