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The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Human hair strength and health are linked to sulfur compounds that can be reduced by stress but improved with sulfur supplements.

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

K18® and Olaplex® both effectively repair bleached hair, improving its strength, smoothness, and overall health.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

Men need higher doses of botox than women and a different approach for facial aesthetics due to their unique facial features and muscle mass.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Protein composition greatly affects the function of keratin biomaterials.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

Alkaline hair relaxers damage hair, but cationic and non-ionic polymers can help reduce this damage.

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.