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FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.

Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

Where a rhesus macaque used to live can affect its chances of getting alopecia later in life, and females are more likely to be affected than males.

Licorice has many health benefits but more research is needed to fully understand them.

A boy with severe immune deficiency and Epstein-Barr virus died from high-grade B-cell lymphoma.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

The document is a detailed medical reference on skin and genetic disorders.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

North American ginseng extract helped regrow hair in balding mice.

Skin symptoms are important for diagnosing infections in children.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.