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GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Innovative methods are reducing animal testing and improving biomedical research.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Balding people may have higher heart disease risk.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.