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The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Hirsutism in teens is often due to polycystic ovarian syndrome and needs careful assessment and support.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Men with Kennedy disease have less chance of hair loss.

Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

Female pattern alopecia is common, starts in late 20s, and is not androgen dependent.