research Hair Growth Effect of Traditional Chinese Medicine BeauTop on Androgenetic Alopecia Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial
BeauTop improves hair growth in androgenetic alopecia patients.
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research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
research Finasteride and Sexual Side Effects
Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
research Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research The 5-Alpha Reductase Inhibitor Finasteride Reduces Dyskinesia in a Rat Model of Parkinson’s Disease
Finasteride reduces movement issues in Parkinson's disease rats.
research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
research Androgenic Alopecia May Have Evolved to Protect Men from Prostate Cancer by Increasing Skin Exposure to Ultraviolet Radiation
Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase
Licorice extract helps hair growth and may treat hair loss.
research Outcome Of Dutasteride 0.5mg In Androgenic Alopecia
Dutasteride 0.5mg improves hair growth in 78% of people with hair loss, but may cause sexual problems in some.
research Androgenetic Alopecia
AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study
Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
research Effects of 5-Alpha Reductase Inhibitors on Erectile Function, Sexual Desire, and Ejaculation
5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
research Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia
Early onset hair loss linked to genetics and androgen levels.
research Pharmacogenetic Analysis of Human Steroid 5α Reductase Type II: Comparison of Finasteride and Dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
research Which Plant for Which Skin Disease? Part 2: Dermatophytes, Chronic Venous Insufficiency, Photoprotection, Actinic Keratoses, Vitiligo, Hair Loss, Cosmetic Indications
Certain plant extracts can effectively treat skin conditions like athlete's foot, chronic vein problems, sun damage, skin growths, vitiligo, and hair loss, and may also improve skin appearance.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Pharmacologic Management of Pattern Hair Loss
Treat pattern hair loss with finasteride and topical minoxidil.
research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
research Androgenetic Alopecia and COVID-19: A Review of the Hypothetical Role of Androgens
Possible link between androgens and COVID-19 severity; more research needed.
research Bioactives in Chinese Proprietary Medicine Modulate 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Classification Scale for Male and Female Androgenetic Alopecia
Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.