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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Some herbs show promise as antiandrogenic agents.

Large prostate links to more hair loss, but age of onset doesn't affect it.

Latanoprost, a glaucoma drug, showed potential for promoting hair growth in bald monkeys, especially at higher doses.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Sex hormones affect brain injury differently in males and females.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Finasteride and minoxidil together work best for male hair loss.

Minoxidil and finasteride combo maintains hair density effectively.

Finasteride and dutasteride effectively stop or reverse hair loss in women with androgenetic alopecia, with dutasteride being more effective for women under 50.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Men with testicular cancer were less likely to experience baldness and severe acne.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Parietal scalp area has lower hair density and smaller hair diameter in women with hair loss.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Optimized film improves finasteride skin absorption and treatment efficiency.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Rats had lasting erectile problems after stopping a certain medication.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.