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research New fluorogenic probes for neutral and alkaline ceramidases

5 citations , March 2019 in “Journal of lipid research”

This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.

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