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5 / 1000+ resultsresearch Updated Integrated Safety Analysis of Ritlecitinib up to ~5 Years in Adolescents With Alopecia Areata From the ALLEGRO Clinical Trials
Ritlecitinib is generally safe for adolescents with alopecia areata over 5 years.
research Updated Integrated Efficacy Analysis of Ritlecitinib Up to 3 Years in Adolescents With Alopecia Areata From the ALLEGRO Clinical Trials
Ritlecitinib is effective long-term for treating alopecia areata in teens.
research Efficacy of Ritlecitinib in Patients with Alopecia Areata by Extent of Hair Loss: Results from the Phase 2b/3 and Phase 3 ALLEGRO Clinical Trials
The study evaluated the efficacy of ritlecitinib, a dual JAK3/TEC family kinase inhibitor, in 191 patients aged ≥12 years with alopecia areata (AA) and ≥50% scalp hair loss. Patients were categorized into severe AA (SALT score 50-94) and very severe AA (SALT score 95-100). At Month 24, 70.2% of patients with severe AA and 54.8% with very severe AA achieved a SALT score ≤20, indicating significant scalp hair regrowth. Eyebrow and eyelash improvements were also observed, with 60.9% of severe AA and 56.5% of very severe AA patients showing eyebrow improvement, and 70.0% and 45.3% showing eyelash improvement, respectively. The study concludes that ritlecitinib 50 mg daily is effective in promoting hair regrowth in patients with severe and very severe AA. The study was funded by Pfizer Inc.
research Medication-induced hair loss: An update
COVID-19 vaccines have been linked to an increase in hair loss conditions.
research Case of de novo nail psoriasis triggered by the second dose of Pfizer-BioNTech BNT162b2 COVID-19 messenger RNA vaccine
The Pfizer COVID-19 vaccine may rarely trigger nail psoriasis.
Community Join
5 / 48 resultscommunity Oral Minoxidil Study of 60 AGA patients
Oral minoxidil treatment increased hair density and shaft caliber in AGA patients. Side effects included hypertrichosis and lower extremity edema, with younger patients experiencing fewer side effects.
community Compunded Oral Minoxidil, As Efficient As Tablet Variants?
The user discusses using compounded oral minoxidil due to the ineffectiveness and inconvenience of topical minoxidil for diffuse thinning. They question the efficacy of compounded minoxidil compared to original tablet forms and express concerns about the importance of excipients and binders.
community Study of thousands of Fin users over 20 years finds no evidence of Fin induced sexual dysfunction
The conversation is about a finding that finasteride does not significantly increase the risk of sexual dysfunction, with users sharing mixed personal experiences regarding side effects.
community Switching from topical min to oral min. Is it the right choice?
The user is considering switching from topical minoxidil to a combined oral treatment of finasteride and minoxidil for better consistency but is concerned about potential side effects like shedding, dizziness, and swelling. Another user advises that oral minoxidil should only be used under medical supervision with regular health checks and suggests using reputable brands like Pfizer's Loniten.
community How to get oral minoxidil in EU?
A user from France is seeking ways to obtain oral minoxidil in the EU without a prescription, as local doctors are hesitant to prescribe it. Suggestions include visiting Spain for a prescription, ordering online, or consulting doctors in other EU countries like Portugal.