May 2025 in “The Journal of Rheumatology” This study reports that even minimal improvements in SLE-related fatigue and skin symptoms are meaningful to patients, supporting the content validity of the FACIT-Fatigue scale for measuring these effects.
September 2022 in “Journal of Investigative Dermatology” This study found that the Severity of Alopecia Tool score does not predict the quality of life in patients with alopecia areata, suggesting patient-reported outcomes better reflect the impact on life quality.
May 2024 in “JEADV Clinical Practice” In this study, researchers found that among patients with severe alopecia areata, a change in SALT scores of 42 or 43 points represents meaningful improvement, highlighting the need to consider individual treatment goals beyond conventional low SALT score targets when assessing treatment benefits.
June 2024 in “Nature Cell and Science” In this research, experienced clinicians noted inconsistency in the reproducibility of the commonly used Hamilton-Ludwig scales for assessing pattern hair loss severity in photographic assessments, leading to the proposal of a new 5-point scale for staging female hair loss.
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March 2025 in “Journal of Clinical Medicine” This study found that Ritlecitinib significantly reduced hair loss in patients with alopecia areata by lowering SALT scores at weeks 12 and 24 compared to placebo, with acceptable safety but increased minor side effects like headaches and acne.