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GlossaryMuscle Atrophy

decrease in muscle mass and strength due to inactivity

Muscle atrophy, also known as muscle wasting, refers to the decrease in muscle mass and strength due to a variety of factors such as prolonged inactivity, aging, malnutrition, or certain medical conditions like ALS or muscular dystrophy. This condition results from an imbalance between protein synthesis and degradation within muscle tissues, leading to the shrinkage and weakening of muscle fibers.

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research Valproate, Acetylcarnitine, Folic Acid, and Vitamin B12 in Spinal Muscular Atrophy: Preliminary Data of an Open-Label Study in Children

1 citations, September 2007 in “Neuromuscular disorders”

The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.

research Spinal and Bulbar Muscular Atrophy: Pathogenesis and Clinical Management

42 citations, May 2013 in “Oral Diseases”

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

research Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat

36 citations, July 2014 in “Neuromuscular Disorders”

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?

17 citations, July 2017 in “Molecular and Cellular Endocrinology”

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients

48 citations, June 2014 in “Neurobiology of Disease”

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

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community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community My conclusive research on Hairline and most other facets of appearance

in Research/Science 10 months ago

The user emphasizes hydration, androgen receptors, and a 7-day ejaculation recovery period for appearance enhancement. They suggest Minoxidil, finasteride, and RU58841 for hair loss, along with a diet rich in animal fats, specific exercises, and fasting.

community My muscles & butt are disappearing on finas, and I’m only taking it because my hair was vanishing too. Help! Details below.

in Finasteride/Dutasteride 7 upvotes 3 years ago

A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.

community What an amazing time to be alive

in Finasteride/Dutasteride 184 upvotes 1 year ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

community Hair Transplant Progress / 3500 Grafts, 9 months on fin and oral minoxidil, should I switch to dut?

in Satire 1878 upvotes 6 months ago

The conversation is about someone's hair transplant progress after 9 months on finasteride and oral minoxidil, considering switching to dutasteride. Specific treatments mentioned include hair transplant, finasteride, oral minoxidil, and a potential switch to dutasteride.

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