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GlossaryLeucine-rich repeat (LRR)

structural motif in proteins involved in various biological processes

Leucine-rich repeats (LRRs) are short sequences of amino acids found in proteins, characterized by the presence of the amino acid leucine at regular intervals. These repeats form a structural motif that creates a horseshoe-shaped domain, which is often involved in protein-protein interactions, playing crucial roles in various biological processes such as cell signaling, immune response, and the development of hair follicles.

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research Expression Level of Leucine-Rich Repeat Containing 15 Regulates Characteristics of Dermal Papilla Cells of Human Hair Follicle

1 citations, September 2020 in “Journal of Dermatological Science”

The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.

research Kin-Cohort Analysis of LRRK2-G2019S Penetrance in Parkinson's Disease

47 citations, June 2011 in “Movement Disorders”

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

research The Expression of Phosphorus-Responsive Genes Is Related to Root Hair Growth

1 citations, April 2009 in “The Proceedings of the International Plant Nutrition Colloquium XVI”

Certain genes may promote longer root hairs in plants when phosphorus is low.

research Clinical Features of Familial Lewy Body Parkinsonism Caused by α-Synuclein Triplication (Iowa Kindred) with Video Documentation

31 citations, June 2011 in “Movement Disorders”

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

research Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy

4 citations, May 2011 in “Movement Disorders”

A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.

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community Any Minoxidil users experience their wife leaving after using for a while?

in Satire 584 upvotes 2 years ago

User's wife filed for divorce after using Minoxidil for 2 weeks. Users joke about Minoxidil causing divorce and suggest other treatments.