January 2024 in “International Journal of Dermatology Research” This study reported a significant association between insulin resistance and acne vulgaris, with a higher prevalence of insulin resistance observed among acne patients compared to healthy controls.
May 2023 in “Research Square (Research Square)” This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.
2 citations
,
January 2019 in “Egyptian Journal of Dermatology and Venereology” This study found no significant differences in insulin resistance between patients with androgenetic alopecia or acne vulgaris and control groups, but suggests insulin may play a role in the conditions' development.
March 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study found that female patients with acne had significantly higher insulin resistance compared to a control group without acne, suggesting that acne could serve as an early clinical marker of insulin resistance in women of reproductive age.
November 2025 in “Cureus” This review discusses the link between PCOS and acne, highlighting the roles of hyperandrogenism and insulin resistance, but it reports no new clinical findings.