research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
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research Prediction of Male-Pattern Baldness from Genotypes
Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.
research Genetic Variants and Lifestyle Factors in Androgenetic Alopecia Patients: A Case-Control Study of Single Nucleotide Polymorphisms and Their Contribution to Baldness Risk
Genetic factors and diet significantly increase the risk of male pattern baldness.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research Repigmentation of Leukoderma in a Piebald Patient Associated with a Novel c-KIT Gene Mutation, G592E, of the Tyrosine Kinase Domain
A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
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5 / 7 resultscommunity Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments
by
diego8895
in Research/Science
14 upvotes
4 years ago Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.
community We Need A Solution For The Inflammatory Response related To AGA
by
ANDR0GENE
in Research/Science
16 upvotes
5 months ago The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.
community M18 Is it smart to start with minox only?
by
Nettspend
in General
126 upvotes
2 months ago An 18-year-old is considering starting minoxidil for hair loss due to a receding hairline but is hesitant about using finasteride due to age and lack of health insurance. A suggestion was made to use topical finasteride and minoxidil, along with lifestyle changes like exercise and cold showers.
community How is it possible for someone to be a non responder to ORAL minoxidil?
by
FlochTheDestroyeer
in Minoxidil
66 upvotes
9 months ago Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
by
Additional_Rough_968
in Research/Science
47 upvotes
2 years ago The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.