34 citations
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June 2011 in “Alcoholism: Clinical and Experimental Research” This study suggests that neurosteroids and compounds acting on GABA(A) receptors, like THIP, may modulate ethanol intake by influencing drinking patterns.
14 citations
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September 2017 in “Hormones and behavior” This study found that the estrous cycle influences the effect of the δ-GABAAR agonist THIP in reducing binge drinking behavior in female mice, with receptor expression elevated during diestrus.
June 2008 in “Alcoholism Clinical and Experimental Research” This study discusses how chronic ethanol exposure and withdrawal affect GABAA receptor subunit expression and function, finding that some changes can be selectively blocked by certain drugs like diazepam and finasteride.