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research The Spectrum of Hair Loss in Patients with Mycosis Fungoides and Sézary Syndrome

39 citations, October 2010 in “Journal of The American Academy of Dermatology”

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity

26 citations, May 2012 in “Cellular and Molecular Life Sciences”

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

research Psychosomatic Aspects of Alopecia Areata

20 citations, August 2018 in “Clinics in Dermatology”

The conclusion is that understanding and addressing the psychological effects of alopecia areata is important for effective treatment.

research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo

6 citations, May 2022 in “Aging”

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis

51 citations, August 2013 in “The Journal of experimental medicine/The journal of experimental medicine”

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

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community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

in Research/Science 3 upvotes 1 month ago

DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 37 upvotes 11 months ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community How far are we from a treatment better than finasteride?

in Treatment 129 upvotes 1 month ago

Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.

community There’s actually a quite good chance that next year, we might see a new treatment get FDA approval for the first time in nearly three decades.

in Research/Science 79 upvotes 1 month ago

Breezula, a potential new hair loss treatment, may receive FDA approval soon, but it is expected to be a weaker alternative to finasteride and minoxidil. Concerns include its twice-daily application and possible side effects like HPA axis suppression.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

in Research/Science 153 upvotes 3 months ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.