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GlossaryQTc interval (Corrected QT interval)

time for heart's electrical system to recharge, adjusted for rate

The QTc interval, or Corrected QT interval, is a measurement on an electrocardiogram (ECG) that represents the time it takes for the heart's electrical system to recharge between beats, adjusted for heart rate. It is important because a prolonged QTc interval can indicate an increased risk of life-threatening arrhythmias, such as Torsades de Pointes.

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research Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer

8 citations, February 2021 in “Journal of the American Heart Association”

Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.

A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

2 citations, May 2021 in “Clinical Pharmacology in Drug Development”

Clascoterone is safe for the heart, even at high doses.

Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

17 citations, August 2019 in “Archives of Cardiovascular Diseases”

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes

9 citations, March 2019 in “European Journal of Sport Science”

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

research Atypical Progeroid Syndrome Due to Heterozygous Missense LMNA Mutations

115 citations, October 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

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community This sub in a nutshell when it comes to medicine. Oral Minoxidil isn’t that bad

in Chat 446 upvotes 1 year ago

The post and conversation are about the use of oral Minoxidil (Min), Finasteride (Fin), and RU58841 for hair loss treatment, with mixed opinions on their safety and effectiveness.

community Hair finally restored after 9 months of taking DUT, Oral Minox, Foam Minox, Zinc, Vitamin D,2% Nizoral, micro needling and much less stress.

in Progress Pictures 72 upvotes 9 months ago

After 9 months of using Dutasteride, oral and foam Minoxidil, Zinc, Vitamin D, Nizoral shampoo, and microneedling, combined with reduced stress, an individual restored their hair. They saw significant improvement despite initial worsening, and had low Vitamin D levels which they corrected with supplements.

community My Vitamin D (25-0H) levels came <4.20 ng/ml (<20 implies deficiency)and B12 came 184 pg/ml (Should be between 211-911). I have a lot of dandruff. The derm has prescribed me with 60k vitamin d tablet once a week and multivitamins for a month. Vitamin deficiency implies TE no? or is it MPB?

in Treatment 38 upvotes 3 years ago

The conversation discusses hair loss treatments, focusing on vitamin D and B12 deficiencies, and mentions using finasteride. It also suggests getting a biopsy to differentiate between MPB and other conditions.

community On a super stack, but still miniaturizationg going strong???

in Update 8 upvotes 2 years ago

User "Number_Worried00" is using a treatment stack for hair loss, including Minoxidil, Finasteride, Dutasteride, Estradiol, Cetirizine, and Pyrilutamide. Another user suggests that if the cause is vitamin deficiency or inflammation, the stack may not be effective.

community Every research project and treatment hope is failing it‘s insane

in Treatment 16 upvotes 5 years ago

The conversation expresses frustration over the lack of progress in hair loss treatments, with specific mentions of Minoxidil, finasteride, and RU58841. Users discuss the slow development of new treatments and the potential of hair transplants.

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