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      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

       447 upvotes 4 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Has anyone used KX-826 as a MONOTHERAPY?

       18 upvotes 4 years ago
      Exploring potential treatments for hair loss, such as Minoxidil, Finasteride, RU58841 and Pyrilutamide. The user is looking for feedback on whether KX-826 can be used successfully as a single therapy to stop the miniaturization process.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Hives/Rash from Kx 826 Pyrilutamide???

       1 upvotes 1 year ago
      OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

      community Can Zinc Affect Finasteride Efficacy?

       6 upvotes 3 years ago
      A 20-year-old male is concerned that zinc might reduce the effectiveness of finasteride for hair loss, as zinc is known to increase DHT levels. Users suggest that zinc, at certain doses, has anti-androgenic properties and is unlikely to negatively impact finasteride's efficacy.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 7 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Pyrilutamide/KX-826 for women?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide/KX-826 is being considered as a potential treatment for female androgenetic alopecia (AGA), but its high cost and limited data on effectiveness are concerns. Kintor markets it for both men and women.

      community KX-826 seems to be working for me

      in Product  1 upvotes 1 year ago
      KX-826 stopped hair loss for the user after stopping finasteride due to mild side effects. The user experienced mild headaches initially with KX-826, which resolved after a few days.

      community Kintor long term safety phase 3

      in Research/Science  66 upvotes 1 year ago
      Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Quercetin with Fin users regarding the synergy of the two.

       3 upvotes 2 years ago
      Finasteride and Quercetin may have a synergistic effect on reducing prostate size, but high doses of Quercetin could negate Finasteride's DHT-lowering effect. Users discuss combining Quercetin with other treatments like resveratrol and topical oils to enhance hair regrowth.

      community Chinese Research Chemicals You Suggest

      in Research/Science  3 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

      community Vitamin D, Zinc, Magnesium supps with Fin?

       1 upvotes 1 year ago
      Taking vitamin D, zinc, and magnesium with finasteride may not counteract side effects like gynecomastia or depression, but they might help if there's a deficiency. Zinc and magnesium could support testosterone levels, and tadalafil is suggested for erectile dysfunction.

      community KX-826 Phase 3 Results Are Out

       121 upvotes 5 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community ZeroMino from Minozidilmax composition

       2 upvotes 3 years ago
      Hair loss discussion involves ZeroMino from Minoxidilmax, with ingredients like Azelaic acid, Adenosine, Biotin, Caffeine, Niacinamide, Retinol, and Melatonin. Company refuses to disclose concentration of ingredients.

      community KX-826: Long-Term Safety Results are out!

       159 upvotes 1 year ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community Kintor’s KX-826 Pyrilutamide!!

       152 upvotes 4 years ago
      KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.

      community Pyrludimide (KX-826) or Breezula (clascoterone)

       9 upvotes 5 months ago
      The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

      community KX-826 Phase 3 Failed. Sorry guys...

       51 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Zinc ANNIHILATED my hair. A cautionary warning.

       4 upvotes 5 years ago
      Zinc supplementation caused significant hair shedding for the user, who had been successfully managing hair loss with finasteride, minoxidil, RU58841, and microneedling. The user discontinued zinc after noticing no libido increase and believes the hair loss was due to zinc's interaction with other minerals or hormonal changes.