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      community Update 1 year and 4 months into medication

      in Progress Pictures  271 upvotes 8 months ago
      The user has been using 1 mg of finasteride since February 2023 and started 2.5 mg of minoxidil at the beginning of the year, and is happy with the improvement in hair loss after 1 year and 4 months of treatment. They are 36 years old and noticed their hair thinning one year ago.

      community How long to see results with treatment? Estimation

      in Treatment  7 upvotes 11 months ago
      The user has been using minoxidil for 3 years but started experiencing hair loss again. They began using fluridil a week ago, noticed less shedding and itching, and are considering whether to wait for fluridil results or start using finasteride as well.

      community Not going to say we told you so, but we did

      in Satire  172 upvotes 1 year ago
      The conversation is about regretting not starting hair loss treatments like finasteride earlier, with some users considering beginning treatment now. Specific treatments mentioned are finasteride (Fin) and minoxidil (Min).

      community Does anyone use Fluridil as their anti-androgen of choice?

      in Chat  6 upvotes 1 year ago
      Fluridil, a non-steroidal anti-androgen approved for alopecia in parts of Europe, is noted for its low side effects but is not commonly discussed. The user is inquiring if anyone prefers it over other anti-androgens like Spiro or RU58841.

      community Frequency/strength of topical minoxidil application

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses the effectiveness of Minoxidil (Min) for hair loss treatment. It concludes that applying a 5% solution once daily is sufficient, and applying it twice daily doesn't provide much more benefit. However, if a higher concentration is beneficial, it can be achieved by more frequent application.

      community HAIR REGENERATION HUMAN TRIALS with Verteporfin

      in Research/Science  11 upvotes 2 years ago
      A new human trial using an FDA-approved treatment for wound healing called Verteporfin, which may potentially be able to reverse scarring and regrow hair in that area. The trial is only lasting one month so far.
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      community Tretinoin for better Minoxidil response

      in Treatment  10 upvotes 3 years ago
      The conversation is about using tretinoin to improve the response to Minoxidil for hair loss treatment. No specific protocol for tretinoin application is provided.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 1 week ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community Best places to get clobetasol?

      in Product  1 upvotes 2 months ago
      The user is considering switching to oral dutasteride, topical minoxidil, retinoic acid, and clobetasol for hair loss treatment, after limited regrowth with finasteride and other topicals. They are seeking a source for clobetasol, as they believe it may help with their condition.

      community minoxidil and tretinoin usage

      in Minoxidil  5 upvotes 2 months ago
      The user is using minoxidil, finasteride, and recently added tretinoin to address hair loss, specifically around a receding hairline. They are seeking advice on application methods and mention experiencing mild skin rashes potentially from tretinoin.

      community Scalp Massages: Has Anyone Found Any Success With This?

      in Female  10 upvotes 3 months ago
      Scalp massages may help with hair loss, but results require significant time and effort, and benefits stop when massages stop. Some users combine massages with topical minoxidil and finasteride for better results.

      community 6 months progress after minoxidil/finasteride stopped working

      in Progress Pictures  19 upvotes 3 months ago
      A 24-year-old with male pattern baldness experienced side effects from oral finasteride and switched to a topical minoxidil/finasteride combination, later incorporating daily shampooing and scalp brushing to manage hair loss and dandruff. After initial shedding, the regimen led to reduced hair loss and new hair growth, with the user now using a densita mf combination (5% minoxidil/0.1% finasteride + redensyl) nightly.

      community Reminder: you can get dutasteride for $6.33 / month in the United States

      in Finasteride/Dutasteride  67 upvotes 3 months ago
      Dutasteride can be obtained for $6.33 per month in the US through Cost Plus Drugs, with prescriptions easily switched from finasteride by contacting a doctor. Users discuss various methods to obtain affordable dutasteride, including using online pharmacies and considering generic options, while cautioning against buying from unreliable sources like eBay.

      community stemoxydine - how much to actually use?

      in Treatment  3 upvotes 3 months ago
      The conversation discusses using stemoxydine for hair loss, with OP considering using 1.5 ml daily despite the recommended 6 ml. Some users doubt its effectiveness, while others report positive experiences using similar amounts.

      community Zero progress and hair slightly getting worse

      in Chat  7 upvotes 5 months ago
      A 21-year-old has been using 1 mg of finasteride and 1 mg of oral minoxidil for 10 months with no progress and worsening hair. They are considering switching to dutasteride and are seeking success stories and advice.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 5 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.