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      community Creating an all-in one topical. Dumb idea?

      in Treatment 2 years ago
      The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.

      community Best way to apply tretinoin?

      in Minoxidil  14 upvotes 3 years ago
      The conversation is about using tretinoin to enhance minoxidil's effectiveness for hair loss, discussing whether to mix tretinoin with minoxidil or apply it separately, and considering the concentration of tretinoin to use.

      community Any long term RU55841 / CB-03-01 / Eucapil users here?

      in Research/Science  10 upvotes 3 years ago
      Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.

      community How much would 10g of CB-03-01-2 (Breezula) last you?

      in Question  6 upvotes 5 years ago
      The conversation is about the use and application of CB-03-01-2 (Breezula) for hair loss, including questions about its form, how to apply it, and the duration 10g would last. Specific treatments discussed are Minoxidil, finasteride, and RU58841.

      community PG causing irritation when applying RU

      in Research/Science 1 year ago
      The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

      community Huge shed after one year Dut when I started RU.

      in Treatment  2 upvotes 1 year ago
      After a year on dutasteride and oral minoxidil, the user experienced significant hair regrowth, improving from Norwood 2 to almost Norwood 1. They added RU58841, microneedling, rosemary oil, GHK-Cu, and annurca apple supplement to their regimen and are now noticing hair loss in the temple area.

      community Anybody else lost a lot of gains on pyrilutamide?

      in Update  8 upvotes 1 year ago
      The conversation discusses hair loss and the ineffectiveness of a treatment called pyrilutamide, with one user experiencing negative results and questioning the product's authenticity.

      community Sublingual topical minoxidil experience

      in Minoxidil  16 upvotes 2 years ago
      A user experienced severe side effects from using topical minoxidil sublingually, including muscle cramps, dizziness, and high potassium levels. They were advised to stop and seek medical help, emphasizing that topical minoxidil is not safe for ingestion due to its alcohol content.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 4 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 7 months ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

      community Estimate of GT20029 on the grey market?

      in Technology  8 upvotes 1 year ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Are 10% fluridil formulations effective?

      in Treatment  6 upvotes 1 year ago
      The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

      community Cosmo Pharma Lists Breezula Phase 3 Trial on ClinicalTrials.gov

      in Research/Science  25 upvotes 1 year ago
      A phase 3 trial for Breezula (clascoterone solution) to treat male pattern hair loss has been listed, with 726 participants and a completion date of January 2025. Other treatments mentioned include Aneira Pharma's combination of minoxidil and latanoprost, Triple Hair's combination of minoxidil, latanoprost, and finasteride, and a new microneedling and LLLT device called StimuSIL.

      community Pyrilutamide users, any updates?

      in Treatment 1 year ago
      Treatment for hair loss, including Pyrilutamide, Minoxidil, Finasteride, and RU58841; with some users reporting success in growing vellus hairs.

      community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

      in Shaved/buzzed  567 upvotes 1 year ago
      This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

      community About GT20029's Efficacy and Strength

      in Chat  6 upvotes 1 year ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  6 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  70 upvotes 1 year ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community What’s the update on Pyrilutamide?

      in Chat  12 upvotes 1 year ago
      Pyrilutamide is seen as a last hope for those who can't take finasteride, with promising results reported. However, there's uncertainty about the quality and consistency of Pyrilutamide from black market sources.

      community Ru58841 2% ED 9 month progress

      in Progress Pictures  17 upvotes 1 year ago
      A user shared their 9-month progress using RU58841 at 2% daily for hair regrowth, initially starting at 5% but reducing the dose due to early signs of gynecomastia, which has since mostly resolved. They achieved their goal of regrowing hair at the temples and hairline.

      community HOW TO pyril powder diy solution

      in Product  8 upvotes 1 year ago
      The conversation is about creating a DIY hair loss treatment solution using pyrilutamide powder, stored in an old minoxidil bottle. The user is seeking advice on how to best replicate Kintor's trials and the ideal storage conditions for the solution.