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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 weeks ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Aggressive diffuse thinning after 1 year of fin and min

      in Progress Pictures  7 upvotes 3 weeks ago
      The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

      community This is what some balding dudes are like

      in Satire  1041 upvotes 3 weeks ago
      Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.

      community 6 months finasteride and 5 months dutasteride

      in Progress Pictures  19 upvotes 1 month ago
      A 22-year-old switched from finasteride to dutasteride for hair loss treatment, also using RU58841, and is managing hypothyroidism. Despite ongoing shedding, they report some improvement and plan to continue dutasteride for a year before considering minoxidil.

      community Is the Ru58841 hype justified?

      in Treatment  17 upvotes 1 month ago
      RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.

      community [24M] 4 month update oral min/fin

      in Progress Pictures  87 upvotes 1 month ago
      The user reported good progress in hair regrowth, especially on the crown, after using oral minoxidil and finasteride for four months and recently switched to dutasteride. The community responded positively, noting realistic progress and offering tips for consistent photo documentation.

      community Discussion on Finasteride and life.

      in Chat  162 upvotes 1 month ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community The "I just want hair until im 30" cope.

      in Chat  221 upvotes 1 month ago
      Participants want to maintain hair until at least age 30, using treatments like finasteride, dutasteride, and minoxidil. Hair loss remains a concern, with some considering hair transplants.

      community I'm sorry I hate it, I cannot enjoy life like this.

      in Chat  175 upvotes 2 months ago
      A 22-year-old male is frustrated about being the only bald person in his social circle. He has tried minoxidil, finasteride, and dutasteride without success and is considering hair systems, transplants, or counseling.

      community "but it will hurt my gains bro"

      in Satire  1303 upvotes 2 months ago
      The conversation humorously discusses hair loss treatments like Minoxidil, Finasteride, and Dutasteride, and their effects on hair and muscle gains. Users debate effectiveness and side effects, mixing scientific approaches with jokes.

      community Sometimes, the problem is the hair structure…

      in Progress Pictures  165 upvotes 2 months ago
      A 24-year-old shared his hair loss journey, using finasteride and topical minoxidil for 6 months with positive results and no side effects. He recommends growing hair out and getting a good haircut to improve appearance and confidence.

      community (20) Found out a coworker likes me, what should I do?

      in Chat  36 upvotes 2 months ago
      A user with aggressive hair thinning is considering how to handle a coworker's interest in them. They are using Minoxidil, Finasteride, and Dutasteride, and are debating whether to keep using hair fibers, shave their head, or get a hair system.

      community Here's the high school I attended. I graduated with a bottle of finasteride.

      in Satire  401 upvotes 2 months ago
      A user humorously shared that someone at their high school gave out finasteride pills, which introduced them to the drug for their receding hairline. The conversation also touched on the high school's location and appearance, with some users joking about their own hair loss and treatments like minoxidil and finasteride.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 3 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community PSA: Caffeine and Hair Transplants

      in Transplants  29 upvotes 3 months ago
      A user shared their experience with a hair transplant, emphasizing the importance of avoiding caffeine 7 days before the procedure. Ignoring this advice led to reduced effectiveness of the numbing agent, causing significant discomfort during the transplant.

      community Embraced baldness. Time to leave this subreddit

      in Chat  866 upvotes 3 months ago
      A user shared their positive experience of embracing baldness after years of trying treatments like Minoxidil and finasteride. They found happiness and confidence by shaving their head, despite some social challenges, and encouraged others to focus on their attitude and seek therapy if needed.

      community My doctor lowered my Minoxidil from 5mg to 2.5mg

      in Minoxidil  71 upvotes 3 months ago
      A user discussed their doctor lowering their Minoxidil dose from 5mg to 2.5mg, expressing concerns about losing hair gains. Other users suggested that 2.5mg is safer long-term and speculated the doctor is being cautious about side effects.

      community Venting My Frustration with Doctors

      in Chat  14 upvotes 3 months ago
      A 22.5-year-old male is frustrated with doctors for not taking his diffuse thinning seriously. He has been using finasteride for 2.5 years, avoids topical minoxidil due to dandruff, and is hesitant about oral minoxidil due to weight and injury concerns.

      community Pérdida de cabello en jóvenes (15-20 años) mi experiencia.

      in Treatment  20 upvotes 3 months ago
      A 19-year-old shares his hair loss experience and treatment routine, which includes 1mg finasteride daily, 2mg oral minoxidil daily, ketoconazole shampoo every 2 days, and a healthy lifestyle. He notes that oral minoxidil is showing better results than topical minoxidil.

      community This sub after taking Finasteride for one day

      in Satire  903 upvotes 3 months ago
      The conversation humorously discusses the side effects of finasteride, particularly sexual dysfunction. Users share mixed experiences, with some reporting issues and others not.