A user's experience with hair loss and their successful hair transplant using finasteride to halt the loss for seven years, as well as other treatments such as Dut and RU58841 being discussed.
The conversation is about disappointment with hair loss progress despite using treatments like finasteride, minoxidil, nizoral, tretinoin, and a dermaroller. Direct sunlight revealed more hair loss than expected, prompting continued treatment and hope for improvement.
The conversation discusses whether a longtime NW7 scalp has vellus hairs under a microscope or is completely smooth. Treatments mentioned include Minoxidil, finasteride, and RU58841.
The user reports the best results for hairline regrowth using 3 drops of minoxidil under the tongue once daily, after trying various treatments including loniten, topical minoxidil with estrogen, dutasteride, and finasteride. Additional regimen includes occasional tretinoin, collagen peptides, crude oil massages, violet ray device, nizoral, and Listerine for scalp health.
Beard hair grown with minoxidil can become permanent because it is not sensitive to DHT, unlike scalp hair, which requires ongoing minoxidil use even with DHT blockers like finasteride or dutasteride. Dutasteride reduces scalp DHT significantly but not completely, which may explain why scalp hair still needs minoxidil for maintenance.
The user experienced significant hair regrowth using Minoxidil (Rogaine) and dermarolling twice a week. They also lost weight and improved their diet, which may have contributed to the results.
The user shared impressive hair regrowth results after 11 months using topical finasteride and minoxidil from HIMS. Many users congratulated the progress and inquired about the application method, brand, and potential side effects.
A person's successful 5-month hair loss treatment using Finasteride and Minoxidil. Questions and comments from others focus on the source of the treatments and application methods.
The conversation discusses the effectiveness of commercial Low-Level Laser Therapy (LLLT) devices for hair growth, suggesting they are underpowered compared to the ideal energy output shown in medical research. A user plans to build a custom helmet that meets the required specifications for effective treatment.
A 27 year old user's progress in treating their hair loss with 1mg of finasteride daily, 2x topical minoxidil daily, micro needling and occasional rosemary oil scalp massage; other users have encouraged the poster based on their results and offered advice for further treatments.
The conversation discusses the fluctuation of testosterone levels in men under 40 and the difference between serum DHT and scalp DHT. It also mentions that DHT levels are higher on Dutasteride than on Finasteride, which is unusual.
A 20-year-old male experienced significant hair regrowth and transformation in under 7 months using oral minoxidil and finasteride. His hair became curlier, darker, and denser, leading to a dramatic change in appearance.
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
User shared a progress photo after 1.5 years of using 1mg Finasteride daily, 5% Minoxidil twice daily, Nizoral shampoo and conditioner 2-3 times weekly, and derma stamping bi-weekly. The post is categorized under "Progress Pictures."
The conversation discusses the positive impact of finasteride and dermarolling on hair loss. The topic is categorized under "Progress Pictures", highlighting the noticeable difference these treatments have made.
A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.
The user shared their 3-month progress using 2.5mg oral minoxidil, 0.5mg dutasteride, 5mg biotin, and a saw palmetto, green coffee, and menthol shampoo, reporting no hair shedding and some unwanted hair growth on the beard and back. They recommend starting with finasteride or dutasteride, especially for those under 18, and noted no side effects from their treatment.
The user improved diffuse thinning without finasteride by using minoxidil foam, cold showers, gentle hair drying, 2% ketoconazole, sulfate-free tea tree oil shampoo, dermastamping, and supplements like Omega-3, Vitamin-D, Biotin, Keratin, Collagen, B3, Zinc, and Magnesium. The regimen was followed for about six months under dermatologist guidance.
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
The user showed a 4-month hair loss treatment progress using topical finasteride with minoxidil, Redensyl, Procapil, Capixyl, ketoconazole shampoo, and occasional microneedling. They took consistent progress photos under the same conditions.
The conversation discusses a 4-month hair loss treatment progress using RU58841, topical Minoxidil, ketoconazole shampoo, and micro-needling. The user shares progress pictures taken at the start, after 1 month, and the current state, all under the same conditions.
A 20 year old male discussing his hair loss regimen, which includes using topical dutasteride, rogaine, RU58841, minoxidil and Avodart pills as well as scalp massage, stabbing head with steak knife, counting shed hairs under a hair net and sending them to a lab for analysis. Suggestions from other users include scalping method and switching to saw palmetto and zinc supplements.
A 25-year-old male shared his 14-month hair regrowth progress using minoxidil, finasteride, and initially dermarolling, along with supplements like fish oil, vitamin D, biotin, and zinc. He attributes his hair loss improvement mainly to the medications and noted minor side effects like lower libido and dark circles under the eyes.
The conversation is about the difficulty in obtaining GT20029, a hair loss treatment, due to patent issues and the need to resort to group buys or Chinese labs for acquisition. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.