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A new hair loss treatment using dermal exosomes can restore up to 90% of lost hair in mice. Users discuss potential human trials and compare it to Minoxidil and Finasteride.

DHT in the scalp, not the bloodstream, is crucial for hair loss. Treatments discussed include finasteride, minoxidil, dutasteride, and microneedling.

The user experienced significant hair regrowth using minoxidil, dutasteride, ketoconazole shampoo, dermarolling, vitamins, and a healthy diet. They reported no side effects and emphasized the importance of consistency.

A 23-year-old male has been using finasteride, dutasteride, and drinking topical minoxidil for almost four months to combat hair loss, seeing reduced shedding and some regrowth. Users advise against drinking minoxidil and suggest that using both finasteride and dutasteride together is overkill.

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

TE (telogen effluvium) is often misunderstood and is triggered by severe stress or trauma, not minor daily inconveniences. Most hair loss cases are due to male pattern baldness (AGA), and treatments like Minoxidil and finasteride can help.

A user speculates that a fast metabolism might affect the effectiveness of dutasteride for hair loss. Another user argues that drug response is unrelated to metabolism speed.

Microneedling at 0.5mm is more effective than at 1mm and 1.5mm for hair loss. Users discuss switching to 0.5mm and combining it with Minoxidil.

The user shared impressive hair regrowth results after 1.5 years using dutasteride (DUT) and oral minoxidil. They switched from finasteride and topical minoxidil due to lack of results and experienced no side effects.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.

A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

A user shared progress pictures after 8 months of using topical 5% minoxidil and 0.01% finasteride, showing significant hair regrowth. Replies suggest the user might not need a hair transplant and recommend considering oral finasteride.

The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

User shared progress after 5 months of using finasteride, minoxidil foam, and weekly derma rolling. Positive feedback highlights increased hair count and thickness.

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

A user is struggling with hair loss at 17 and has been using finasteride for 5 months and minoxidil for 11 months without seeing regrowth. Other users encourage continuing treatment, sharing their own experiences with finasteride, minoxidil, and dermarolling, and emphasizing patience and acceptance.

A user reported no improvement in hair loss after nearly a year of using 1mg oral finasteride, topical minoxidil twice daily, and weekly microneedling. Other users suggested the possibility of DUPA or retrograde alopecia and mentioned that treatments might only slow down hair loss rather than regrow hair.

A user gained 10-12 kg after starting finasteride but found their estrogen levels to be within the normal range. They are concerned about potential gynecomastia but are reassured by their lab results.

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

Joe Biden aged significantly between ages 25 and 30, with noticeable changes in hair and facial features. He had a hair transplant, but it's unclear if he used Minoxidil or Finasteride.

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

A user started taking finasteride for hair loss despite initial fears. Others shared their positive experiences with finasteride and dutasteride, encouraging the user.

User shared 12-month hair loss progress using oral minoxidil, oral dutasteride, and 2% ketoconazole shampoo. They detailed their medication regimen and dosages.

A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

A user shared their experience with finasteride, noting improved hair thickness but reduced libido and erection issues. They stopped finasteride, saw a return of libido but also rapid hair loss, and are now considering using Cialis to manage sexual side effects while on finasteride.