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      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 4 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community Can I Use Topical Azelaic Acid & Oral Finasteride At The Same Time?

      in Minoxidil  2 upvotes 6 months ago
      A user is considering using a topical Minoxidil solution with tretinoin and Azelaic Acid while taking oral Finasteride and is seeking advice on safety and effectiveness. They have been using Minoxidil for 10 years with mild results and oral Finasteride for a year with some positive changes.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 6 months ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Finasteride increase in Estradiol?

      in Update  17 upvotes 7 months ago
      A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.

      community 4 months topical min and 1,5 months topical fin. Also microneedling almost every week. Do you see a difference?

      in Progress Pictures  53 upvotes 9 months ago
      The conversation discusses a user's 4-month progress using topical minoxidil and 1.5-month use of topical finasteride, along with almost weekly microneedling, for hair loss. Some responses indicate noticeable improvement and encourage continued use, while others suggest it's too early to judge effectiveness and mention the possibility of a hair transplant.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  52 upvotes 10 months ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Should I start fin with these blood tests?

      in Finasteride/Dutasteride 10 months ago
      A 25-year-old male is concerned about his blood test results, particularly the low percentage of free testosterone, and is questioning whether starting finasteride for hair loss might worsen this issue. He also notes a slight vitamin D deficiency and lack of sleep before the test.

      community M22 1 year 4 months topical min + oral fin

      in Finasteride/Dutasteride  216 upvotes 11 months ago
      A user's experience with hair loss treatments, specifically Minoxidil (topical) and Finasteride (oral), over a period of 1 year and 4 months. The user reported best results after 6 months, a significant hair shed 4 months ago, and current regrowth, while also using a 1.25mm dermastamp. The user adjusted Finasteride dosage over time and experienced high testosterone and nipple sensitivity.

      community 28yr old 5mg minoxidil daily, .5 dutasteride every 2 days

      in Progress Pictures  11 upvotes 1 year ago
      A user started using 5mg minoxidil daily and 0.5mg dutasteride every two days for hair loss, along with rosemary, castor, and pumpkin oil twice a week, and derma stamping once a week. They plan to track progress with photos and maintain hair length with clippers.

      community From June 22 to August 23 slowww progress

      in Progress Pictures  13 upvotes 1 year ago
      The conversation is about a person's slow progress in treating hair loss using finasteride, microneedling, testosterone replacement therapy, dutasteride, RU58841, and minoxidil. They experienced a significant hair shed after adding dutasteride.

      community Why is there more "fear" around on finasteride than around dutasteride

      in Chat  18 upvotes 1 year ago
      The conversation is about the comparison between finasteride and dutasteride for hair loss treatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community Rosemary oil, peppermint oil, mucuna pruriens - two weeks in

      in Treatment  86 upvotes 1 year ago
      A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

      community Kintor’s GT20029 Phase 1 success

      in Update  74 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community My progress for 1 year minoxidil and dutasteride mesotherapy

      in Progress Pictures  101 upvotes 1 year ago
      A user's progress using minoxidil and dutasteride mesotherapy to treat hair loss, with advice from other users on whether or not to continue the treatment. Suggestions included trying oral treatments such as finasteride and RU58841, and considering a hair transplant for more significant results.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.