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      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 1 week ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community 1 year on fin and min results

      in Progress Pictures  47 upvotes 4 years ago
      The user has been using finasteride and minoxidil since September 2019 and has seen significant hair regrowth. Their routine includes a compounded topical with minoxidil, finasteride, dutasteride, and retinol at night, and 1mg finasteride in the morning.

      community Yeah, it’s working 👍🏻 Nov 2023 to March 2024

      in Progress Pictures  61 upvotes 7 months ago
      Animajax, who started off completely bald, has seen hair regrowth using finasteride 1.25mg, oral minoxidil 2.5mg, occasional topical minoxidil, dermastamping, benzoyl peroxide, and tretinoin. They recently added nizoral and plan to switch to a topical solution combining minoxidil and dutasteride.

      community Adding topical dutasteride to my stack

      in Treatment  6 upvotes 6 months ago
      A 38-year-old woman has been using oral Dutasteride for a year without improvement and is now adding a topical solution containing Minoxidil, Dutasteride, Tretinoin, Ketoconazole, and Hydrocortisone. She is seeking advice on whether switching from oral to topical Dutasteride could prevent hair shedding.

      community About 9 Months on Topical Fin/Min

      in Progress Pictures  585 upvotes 3 years ago
      User shares 9-month progress using topical Fin/Min formula (10% Min, 0.1% Fin) for hair loss, with significant improvement in crown area. Others discuss experiences, side effects, and application methods for the treatment.

      community Topical melatonin/oral

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.

      community Homemade topical spironolactone

      in Research/Science  26 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community Is Topical Fin a Reasonable Alternative?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      A user discusses mild/moderate hair loss and considers switching from oral to topical finasteride due to past endocrine issues. They seek feedback on topical finasteride's effectiveness and reputable sources, with replies suggesting Minoxidilmax products as effective alternatives.

      community 3 months on minoxidil 5% twice daily and micro microneedling, 2 months on topical finasteride (every other day) and bunch of supplements here and there.

      in Progress Pictures  106 upvotes 7 months ago
      The user has been using minoxidil 5% twice daily, micro-needling, topical finasteride every other day, and various supplements for 3 months to treat hair loss and has seen positive results. They also mentioned using hair growth tablets, biotin, zinc, and vitamins B and D, but not consistently.

      community 17 month update 30M FUT 2300 grafts 1 year fin/min topical

      in Progress Pictures  414 upvotes 8 months ago
      A user shared a 17-month update on their hair loss treatment, which included a hair transplant of 2300 grafts, using a topical solution of minoxidil and finasteride, a laser cap, and ketoconazole shampoo. They are considering another transplant and seeking honest feedback on their progress, while others share their own experiences and advice on hair loss treatments.

      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  52 upvotes 3 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

      community where does the renewed spironolactone hype come from?

      in Research/Science  7 upvotes 1 year ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community Will minoxidil not work if there’s too much DHT present in the scalp?

      in Minoxidil  5 upvotes 8 months ago
      The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 6 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community 32 M 1 year anniversary on Fin

      in Progress Pictures  155 upvotes 6 months ago
      A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.

      community does dermarolling work with oral minoxidil?

      in Microneedling  9 upvotes 3 months ago
      The conversation discusses whether dermarolling (microneedling) works with oral minoxidil for hair loss treatment. References to studies on microneedling alone and combined with minoxidil are provided.

      community bye fellas, it’s time to quit this sub

      in Progress Pictures  810 upvotes 6 months ago
      A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.

      community Been battling for 4+ years and still getting worse

      in Chat 11 months ago
      The user has been experiencing hair loss for over 5 years and is currently using a topical treatment of finasteride, minoxidil, and tretinoin, along with derma rolling and a hair growth oil. They have previously tried oral finasteride, pyrithione zinc, RU58841, and dutasteride, but are seeking advice on whether to retry dutasteride or find a more reliable source for RU58841 due to ongoing hair density loss.

      community How long still for CB-03-01? (breezula)

      in Question  7 upvotes 4 years ago
      The conversation is about the release timeline for clinical trial results and the availability of Breezula, a hair loss treatment. The user is not comfortable buying it as a research drug from China.

      community Hair loss treatment tier list by Dr Oscar Muñoz

      in Treatment  913 upvotes 3 months ago
      Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 1 year ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community 6 months on the sauce- Min,Fin,DR

      in Progress Pictures  633 upvotes 1 year ago
      A user's successful 6-month journey with Minoxidil, Finasteride and 0.05 Derma Rolling to regain their hairline, eyebrows, facial hair and overall youthful look. They also discussed the use of topical minoxidil for eyebrow thickening, as well as other skincare routines and healthy lifestyle habits.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.