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GlossaryTransforming Growth Factor Beta (TGF-B)

protein regulating cell growth, differentiation, and immune responses

Transforming Growth Factor Beta (TGF-β) is a protein that plays a crucial role in regulating cell growth, differentiation, and immune responses. It is involved in various biological processes, including wound healing and the development of fibrosis, and can influence hair growth by affecting the hair follicle cycle.

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community Does Finasteride Sustain Minoxidil-grown Hairs?

Beautiful_Dogs_ in Finasteride/Dutasteride 8 upvotes 1 year ago

The post discusses whether finasteride can maintain hair growth stimulated by minoxidil. The response indicates that finasteride cannot sustain minoxidil-grown hairs.

community Why is nobody studying the difference between donor and balding hair?

Hairlssuf in Chat 89 upvotes 8 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community If Minoxidil Beards are permanent, why should Finasteride be unable to keep Minoxidil Gains on the scalp?

sziyo in Minoxidil 104 upvotes 2 years ago

Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.

community The Effect of Intradermal Botox on Androgenetic Alopecia and Its Possible Mechanism (Journal of the American Academy of Dermatology (2020)

TerpsandCaicos in Treatment 12 upvotes 4 years ago

Intradermal botulinum toxin (BTX) injections effectively treat androgenetic alopecia (AGA) by inhibiting TGF-β1 secretion from hair follicles. Further research and long-term follow-up are needed to confirm these findings.

community Finally Managed to Download Somebody's Alex pdf so try to share it

Sorry_Alex_ThrowAway in Research/Science 70 upvotes 11 months ago

The conversation discusses a shared PDF about hair loss treatments, which might help those not seeing results with Minoxidil, Finasteride, and RU58841. Some users are skeptical about the content's value and the price charged for it.

community Natural Remedies: Polyphenols and Hair Loss

jrz302 18 upvotes 5 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

community Update on my Derma Roller and Essential Oils Experiment.

BarkingMad14 in Microneedling 9 upvotes 3 years ago

A user is experimenting with a hair loss treatment involving derma rolling and essential oils, avoiding expensive treatments and medications. They plan to shave their head, use a derma roller three times a week, apply Nizoral twice a week, and use a mix of Rosemary, Peppermint, and Jojoba Oil on non-rolling days.

community Possible topical option for preventing BDNF-related hair loss

Wearethemusicmaker in Research/Science 7 upvotes 1 year ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community Pirfenidone - The answer to fibrosis and baldness

uttftytfuyt in Treatment 19 upvotes 3 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Hairloss - what hormones to check?

engineer_pt in Finasteride/Dutasteride 10 upvotes 1 year ago

The user is concerned about hair loss despite using oral finasteride, oral minoxidil, and topical minoxidil. They are seeking advice on additional blood tests to identify potential causes.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

DSBarreto in Research/Science 40 upvotes 6 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Pyrilutamide update: three months

Immortal_lunch66 in Update 33 upvotes 2 years ago

A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

community Boys how is no one seeing positive results from pyrilutamide

longjonsilver55 in Chat 28 upvotes 2 years ago

Pyrilutimide, a treatment for hair loss; it's effectiveness compared to other treatments such as Finasteride and RU58841; and some users’ experiences with the treatment.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

Villanellat in Research/Science 117 upvotes 1 year ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community Tretinoin potentially can make hair loss worse ?

Number_Worried00 in Research/Science 6 upvotes 2 years ago

Tretinoin may worsen hair loss by inducing premature hair follicle regression. It can be used with minoxidil to increase absorption but should not be used alone.

community dunno if it's growing anything but it's making my scalp red

manbearpot in Technology 182 upvotes 1 year ago

Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

milofam in Treatment 51 upvotes 2 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

community SAFFLOWER OIL good alternative for Minoxidil?

Kaiox9000 in Treatment 1 upvotes 5 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community Is this broscience? From More Plates, More Dates

Top-Astronaut4004 in Research/Science 21 upvotes 11 months ago

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

community Taurine supplements work for hair growth?

SileDub in Product 8 upvotes 9 months ago

The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

community My hairloss journey. Minox at 34, transplant at 38. No Finasteride

Awkward-Zebra in Transplants 267 upvotes 10 months ago

A person started using Minoxidil at 34 and had a hair transplant at 38, avoiding a straight hairline for a natural look and had 2200 grafts. They began taking Finasteride as a precaution, but Minoxidil did most of the work.

community Proposed new pathogenesis model for androgenetic alopecia (AGA)

randomuser_aga in Research/Science 8 upvotes 1 year ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Scientists have finally found the potential ‘cure’ for baldness

sadFruits in Research/Science 2 years ago

A new study that found a single chemical could potentially be responsible for hair loss, and the potential to use this discovery to stimulate hair growth. The conversation also includes various treatments such as Minoxidil, Finasteride, RU58841, microneedling, DUT, and Botox for hair loss.

community Topical Finasteride update by H&W

throwmeawayforever9 in Finasteride 28 upvotes 7 years ago

The conversation discusses using topical finasteride for hair loss, with concerns about its safety around family members, especially pregnant women and infants. One user plans to try topical finasteride due to side effects from the pill.

community Fevipiprant 2019!

Folliman 17 upvotes 8 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community 5 Month's progress on Topical FIN, MIN, Topical Dut, Laser Cap

hemantch in Progress Pictures 577 upvotes 3 years ago

User "hemantch" shares 5 months progress using topical Fin, Min, topical Dut, and a laser cap for hair loss. Significant regrowth was noticed after 1 month, and the treatments worked well despite being bald for 10 years.

community UPDATE: The theory that explains everything. Please help me make this big!

joaopassos4444 in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Comprehensive Microneedling Guide

throwoveraccount in Microneedling 294 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

MENSCRIPT in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

noeyys in Research/Science 72 upvotes 7 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.