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      community Yo!! One year update chooms!!!!

      in Progress Pictures  2796 upvotes 1 week ago
      Significant hair regrowth was achieved using 0.5mg oral finasteride, a topical mix of finasteride and minoxidil, and dermastamping. Initial side effects like achy testicles were managed by adjusting the regimen.

      community Low dose spiro with 5ARI inhibitor

      in Chat  2 upvotes 2 months ago
      Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.

      community What the hell does it mean by “do not apply to front of scalp”

      in Minoxidil  24 upvotes 2 months ago
      Minoxidil can be applied to the entire scalp, including the hairline, despite labels suggesting otherwise due to lack of specific testing. For best results in treating hair loss, combining minoxidil with finasteride is recommended, as finasteride addresses the underlying cause of male pattern baldness.

      community 3 months update on meds post HT

      in Progress Pictures  111 upvotes 3 months ago
      The user started using 1mg finasteride and Regaine foam post-hair transplant, noticing significant hair growth at three months. They experienced testicular cramps as a side effect but no other issues, and are considering microneedling for further improvement.

      community Insane Idea: Cyperus Rotundus Oil?

      in Research/Science  9 upvotes 4 months ago
      Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hair growth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.

      community Question about medications ...

      in Finasteride/Dutasteride  2 upvotes 4 months ago
      Hair loss treatments like spironolactone often require lifelong use to maintain results. Stopping the medication can lead to increased testosterone levels and potential hair loss.

      community Recommended AHK-Cu peptide brand?

      in Treatment  1 upvotes 4 months ago
      AHK-Cu peptide is considered better than GHK-Cu for hair growth. The user is seeking recommendations for trusted AHK-Cu peptide brands with third-party testing.

      community Shedding on pyri (KX-826) is this normal?

      in Update  10 upvotes 6 months ago
      A user experienced increased shedding after adding KX-826 to their long-term finasteride and minoxidil regimen. Another user reported mild side effects from KX-826, such as stomach and testicle pain.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 6 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community What blood exams should I do on dut/oral min

      in Chat  1 upvotes 7 months ago
      The user checked iron, ferritin, B12, zinc, testosterone, DHT, and estrogens to understand hair loss causes and the effects of dutasteride. They also noted increased heart rate and paleness with oral minoxidil.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 7 months ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

      community Topical Spironolactone 5% effectiveness

      in Product  2 upvotes 7 months ago
      Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 9 months ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community 52M completed my first 30 day on 5% topical Minoxidil

      in Progress Pictures  37 upvotes 11 months ago
      A 52-year-old man has been using 5% Minoxidil twice daily for 30 days to treat hair loss, alongside 2.5mg Finasteride, which he reduced from 5mg despite his doctor's advice. He has a history of hair loss due to testosterone treatment and hopes to see improvement in the crown area of his scalp.

      community Probably progress in about 4 months

      in Progress Pictures  47 upvotes 11 months ago
      The user started using minoxidil and finasteride for hair loss but stopped minoxidil due to scalp issues and tinnitus. They experienced testicular pain, shedding, and side effects like itchy chest and watery sperm, but noticed considerable hair regrowth except at the temples.

      community Reasonable and safe stack? Bloodwork within.

      in Minoxidil  1 upvotes 11 months ago
      A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 1 year ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Hairloss - what hormones to check?

      in Finasteride/Dutasteride  10 upvotes 1 year ago
      The user is concerned about hair loss despite using oral finasteride, oral minoxidil, and topical minoxidil. They are seeking advice on additional blood tests to identify potential causes.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 1 year ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.