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Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

Breezula protects hair follicles from both testosterone and DHT, unlike finasteride, which only protects against DHT. This could potentially lead to significant hair regrowth, similar to results seen in transgender individuals using hormone blockers.

A user on finasteride for 7+ months shared bloodwork results, questioning if high DHT levels and testosterone could affect cholesterol. Replies suggest consulting a doctor and question the high testosterone levels.

The user has been using finasteride and oral minoxidil for hair loss but hasn't seen improvement and is quitting nicotine and caffeine to see if it helps. Some believe quitting nicotine improved their hair health due to better blood flow, while others are skeptical about the impact of blood flow on hair loss.

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

The relative strength of Pyrilutamide compared to RU58841 in terms of androgen receptor binding affinity. It has been noted that Pyrilutamide is 4x stronger than RU58841, with a higher binding affinity than DHT itself.

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

A user experiencing hair loss despite using finasteride, minoxidil, and tretinoin. They're considering trying dutasteride or shaving their head if the situation doesn't improve.

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

Person 1, with slow hair loss, might need less finasteride than Person 2, who is balding rapidly. The suggested doses are 0.25 mg finasteride three times a week for Person 1 and 1 mg daily for Person 2.

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

The conversation is about the effects of grape seed extract on hair, with mixed experiences reported. One user advises against using it.

A user experienced increased hair density loss after 4 months on dutasteride combined with finasteride. They are also using topical dutasteride with azelaic acid and alfatradiol but cannot tolerate antiandrogens like RU58841 due to headaches.

A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

A 22-year-old has seen hair density improvement after using oral minoxidil 2.5mg daily for 7 months and also uses rosemary mint oil weekly. Others suggest finasteride for long-term results, question minoxidil's effectiveness without finasteride, and mention alternatives like microneedling.

The conversation discusses a hair regrowth protocol involving Dutasteride, Pyrilutamide, Stemoxydine, Minoxidil, Tretinoin, Oral Castor Oil, and L-Carnitine L-Tartrate. Some users are skeptical, particularly about the effectiveness and side effects of oral castor oil.

RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.

User experienced hair growth after 4 months using Minoxidil and dermastamp. Others suggest adding Finasteride or Dutasteride for long-term results and trying microneedling with Minoxidil.

User experienced hair growth after 6 months using microneedling, minoxidil, ketoconazole, and biotin. Commenters suggest adding finasteride to treatment for better results and preventing further hair loss.

Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.

Female, 28, losing hair since 17, using 200mg Spiro. Tried Minoxidil and ketoconazole with limited success, considering oral minox and seeking alternative treatments from cosmetic dermatologist.

Female considering adding topical anti-androgen, seeks advice on RU58841 or pyrilutamid's binding affinity compared to spironolactone.

Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

A user shared their one-year progress using finasteride 1mg three times a week, starting at age 25, with noticeable regrowth after three months and no side effects. Other users discussed their experiences with finasteride, minoxidil, microneedling, and dutasteride, noting varying results and side effects.

Dutasteride improved the user's hair thickness and health, slowed body and facial hair growth, and enhanced skin condition. The user also reported feeling energetic with a slight decrease in libido but no issues with sexual function.