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      community Homemade topical spironolactone

      in Research/Science  26 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community What’s the deal with pyrilutamide?

      in Research/Science  52 upvotes 2 years ago
      The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 3 weeks ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 5 months ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

      community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

      in Technology  105 upvotes 1 year ago
      The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

      community I experimented with every medication for hair loss for at least 1 year. my thoughts.

      in Treatment  66 upvotes 2 years ago
      Minoxidil effective for regrowth but causes dryness; finasteride stops hair loss but may affect hormones; dutasteride powerful but reduces libido; RU58841 thickens hair but expensive and risky; dermarolling improves blood flow and results; aminexil overrated and not effective. Dermarolling beneficial with both minoxidil and finasteride.

      community The best stack that doesn't include a 5ARI

      in Treatment  10 upvotes 1 year ago
      The conversation is about finding effective hair loss treatments without using finasteride or dutasteride. Suggested treatments include topical minoxidil, oral minoxidil, microneedling, PRP, and RU58841.

      community Hair loss treatment tier list by Dr Oscar Muñoz

      in Treatment  913 upvotes 3 months ago
      Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

      community How do we only have two treatments to combat hair loss at this point in time?

      in Chat  211 upvotes 1 year ago
      The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

      community Is Eucapil (fluridil) actually legit?

      in Treatment  7 upvotes 2 years ago
      User asks about Eucapil (fluridil) for hair loss, its effectiveness, safety, and where to buy in Australia. Others share experiences and purchase options.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 1 year ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Success with just Fin + Dermarolling

      in Advice  15 upvotes 5 years ago
      The user has been using finasteride for 5 months without hair regrowth or loss and is considering adding dermarolling to their regimen. They are seeking advice on the effectiveness of finasteride with dermarolling, the type of dermaroller to use, aftercare products, and concerns about shedding from dermarolling alone.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 8 months ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

      community Can RU58841 stop hairloss for a long time?

      in Research/Science  11 upvotes 11 months ago
      A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.