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      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

      in Research/Science  110 upvotes 10 months ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community Where to Begin with Microneedling?

      in Treatment  17 upvotes 10 months ago
      User is considering microneedling to enhance hair regrowth after limited response to minoxidil and better results with finasteride and ketoconazole shampoo. Recommendations include using a 1.5mm derma roller once a week, avoiding minoxidil on microneedling days, and disinfecting the roller with isopropyl alcohol.

      community 3 months on Hims Topical Spray

      in Progress Pictures  429 upvotes 10 months ago
      The user has been using Hims finasteride and minoxidil spray, nizoral shampoo twice a week, and a daily biotin gummy for 90 days to treat hair loss. The user and others discuss the cost, dosage, and effectiveness of the treatment, with some suggesting cutting hair short for better results.

      community Are these all the anti androgen products?

      in Treatment  6 upvotes 11 months ago
      The conversation lists hair loss treatments including finasteride, dutasteride, RU58841, pyrilutamide, breezula, and fluridil, and suggests ketoconazole as another option. Some users warn against using certain treatments like cyproterone acetate, bicalutamide, and spironolactone due to their strong anti-androgen effects and potential impact on masculinity.

      community CAUTION: My Experience with RU58841

      in Treatment  14 upvotes 11 months ago
      The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

      community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

      in Technology  108 upvotes 11 months ago
      The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

      community Losing hair as teenager Dont know what to do

      in Chat  3 upvotes 1 year ago
      A teenager started balding at 13 and has been using minoxidil for 2 years, but the hair loss is returning. They are seeking advice on additional treatments. Another user suggests finasteride or shaving the head, and emphasizes the importance of not letting hair loss affect self-esteem and relationships.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community What’s your nuclear protocol???

      in Chat  21 upvotes 1 year ago
      People discussed their intense hair loss treatments, including the use of dutasteride, RU58841, minoxidil, tretinoin, essential oils, microneedling, and various topical sprays. Some users reported success with these methods in preventing hair loss and stimulating hair growth.

      community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

      in Treatment  27 upvotes 1 year ago
      The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

      community Should I start Fin with these blood tests?

      in Finasteride/Dutasteride  16 upvotes 1 year ago
      A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

      community Goodbye y'all, it's been a journey but have accepted where I'm at

      in Update  219 upvotes 1 year ago
      The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

      community What do we actually know about HMI-115?

      in Chat  16 upvotes 1 year ago
      The post and conversation are about HMI-115, a potential treatment for hair loss. The conclusion is that HMI-115 is not a 5ar-inhibitor and is instead a prolactin receptor inhibitor. Some users are skeptical about its effectiveness and believe that baldness will still be a problem in the future.

      community Why is there more "fear" around on finasteride than around dutasteride

      in Chat  18 upvotes 1 year ago
      The conversation is about the comparison between finasteride and dutasteride for hair loss treatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.

      community Bryan Johnson’s Hairloss Regimine

      in Research/Science  25 upvotes 1 year ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.