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GlossarySynthetic Polymers

large molecules engineered from chemically bonded smaller units

Synthetic polymers, also known as man-made or artificial polymers, are large molecules created through the chemical bonding of smaller units called monomers. These polymers are engineered in laboratories and industrial settings to have specific properties and uses, such as in the production of plastics, synthetic fibers, and various medical applications. Examples include nylon, polyester, and polystyrene.

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community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Has anyone here tried topical synthetic prostaglandins (Bimatoprost, Latanoprost, cetirizine) to stimulate hair growth?

in Treatment 7 upvotes 1 month ago

The conversation discusses using topical synthetic prostaglandins like Bimatoprost, Latanoprost, and cetirizine for hair growth. The user shares a link suggesting these treatments may be effective.

community ASC-J9: Poor man’s GT-20029 that might work for regrowth. Anyone try this stuff?

in Research/Science 1 year ago

The potential hair regrowth benefits of ASC-J9, a synthetic modified version of curcumin that is said to be more effective than Minoxidil and Finasteride. Reports from users suggest good thickening and temple regrowth with topical use at 0.025% concentration.

community Collagen/Vitamins/Supplements and skin-care routine while on Minoxidil?

in Minoxidil 29 upvotes 4 years ago

Minoxidil users discuss skin-care routines to counteract side effects like dark circles and dull skin. Recommendations include vitamin C, potassium, collagen, retinol, nizoral shampoo, and emu oil.

community medication for hair loss spironolactone

in Female 3 upvotes 1 year ago

41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2597 upvotes 2 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

community 8-9 Month Update. 24M Korean Diffuse Thinner

in Progress Pictures 311 upvotes 8 months ago

The conversation discusses a 24-year-old Korean man's progress with hair loss treatments over 8-9 months, with specific treatments not mentioned due to redacted information. Users are commenting on the effectiveness and inquiring if Asians have better results with hair loss treatments.

community I'm gonna be bald by 20 and I'm not even exagerrating. Wtf do I even do?

in Chat 77 upvotes 1 year ago

A 16-year-old is experiencing early male pattern baldness and is considering using Minoxidil now and Finasteride after turning 18. Another user shared a positive experience with topical Minoxidil and Finasteride, noting improvement in hair thickness and no side effects.

community Scientific Review: Saw Palmetto is not effective for treating hair loss and does not inhibit DHT to the extend that most people think. Anti-Hair loss claims are invalid.

in Research/Science 34 upvotes 2 years ago

Saw Palmetto is not effective for hair loss treatment and is not a recommended alternative to finasteride due to its inability to significantly inhibit DHT.

community Topical T3 study - 1000% Growth. Anyone tried it?

in Research/Science 106 upvotes 3 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

community The Hormonal Profile of MPB/AGA

in Research/Science 8 upvotes 3 years ago

Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community How soon is hair clone? Next five years?!

in Research/Science 15 upvotes 3 months ago

Hair cloning is humorously discussed as always being 5-7 years away, with skepticism about its near-term availability. Gene editing to reactivate dormant follicles is suggested as a more likely solution within the next ten years.

community Exploring Bryan Johnson's Hair Routine In Detail

in Research/Science 63 upvotes 8 months ago

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

community If Ru58841 was an FDA approved medication and known to be safe would you recommend it before finasteride?

in Product 7 upvotes 10 months ago

The conversation discusses whether RU58841, if FDA approved and safe, would be recommended over finasteride for hair loss. Specific treatments mentioned include RU58841, finasteride, and minoxidil.

community So i am using ru and pyrilutamide both lol, and one of them is definitely working, i am getting hairline back which was previously completely gone, like that 18 year old hairline, but its so fucking slow, if you care about hair start now, its much easier to hold than regain.

in Update 60 upvotes 1 year ago

A user is using RU58841 and pyrilutamide for hair loss and is seeing their hairline return, but the process is slow. They also mention using finasteride and dutasteride, with finasteride causing reduced libido but no noticeable side effects from RU58841 or pyrilutamide.

community Overwhelming amount of anti-androgens

in Female 1 year ago

The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

community Organic Self Tanner on bald Scalp?

in Shaved/buzzed 1 upvotes 1 year ago

The user is using topical minoxidil and finasteride, along with daily derma rolling, and is considering using an organic self-tanner on their shaved scalp. They seek advice on whether the self-tanner's ingredients could harm hair regrowth.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Pyrilutamide vs Ru58841 thoughts

in Research/Science 8 upvotes 1 year ago

The user has been using Pyrilutamide (Pyril) for hair loss for a month alongside finasteride/dutasteride since 2021 but hasn't seen results. They are considering switching to RU58841 due to its many success stories, despite being skeptical about the legitimacy and testing of Pyrilutamide.

community 4 months minox + fin +microneedling

in Progress Pictures 336 upvotes 1 year ago

A user's progress with treating hair loss, using minoxidil, finasteride and microneedling. The user experienced impressive results after four months of treatment, and mentioned that stopping recreational drugs and losing weight helped their hair regrowth.

community When you add Pyril to the 100 other things you take for hair

in Satire 75 upvotes 2 years ago

Treating hair loss with finasteride, dutasteride and minoxidil, as well as micro-needling, potentially using research chemicals such as Pyril and Senzu Beans.

community Has anybody tried retinol (not Retin A aka tretinoin) combined with minoxidil?

in Treatment 20 upvotes 2 years ago

The conversation is about someone who had success using retinol with minoxidil for hair growth, but experienced shedding with Retin A (tretinoin). They are asking if others have tried retinol with minoxidil and what their results were.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 2 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.

community Microneedling as monotherapy? Combined with castor-, peppermint- and rosemary oil + coffein. Does it work?

in Microneedling 12 upvotes 2 years ago

The conversation discusses using microneedling combined with castor, peppermint, rosemary oils, and caffeine as a treatment for mild hair loss, aiming to stop or slow down hair loss and potentially regrow hair. The effectiveness of this treatment without side effects is uncertain, and it may slow hair loss but results vary.

community Please stop looking for a natural way to stop your hairloss

in Chat 369 upvotes 3 years ago

No natural way to stop hair loss, pharmaceuticals only option. Users discuss Minoxidil, Finasteride, natural remedies, and healthy scalp importance.

community Vitamin E

20 upvotes 5 years ago

Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.

community Why are wigs normalized for women and not men? Shouldn't it be the other way around?

in Chat 268 upvotes 2 weeks ago

Men wearing wigs should be normalized as it is for women. Treatments like Minoxidil and finasteride are mentioned, but societal norms need to change to accept wigs for men.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 2 months ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 41 upvotes 2 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 70 upvotes 2 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.