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      community Treatment isn't working? Stay the course.

      in Treatment  1 upvotes 6 days ago
      The user tried finasteride for a year without success, then switched to dutasteride and oral minoxidil for 10 months, still experiencing hair loss. Adding RU58841 and topical minoxidil seemed to improve their condition, with new hair growth observed.

      community Is this good improvement? 3-4 months in

      in Is this regrowth?  473 upvotes 1 week ago
      The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.

      community 2Y 5M on dut, ask me anything

      in Finasteride/Dutasteride  125 upvotes 1 week ago
      A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

      community 1ish year on fin and no improvement

      in Is this regrowth?  86 upvotes 2 weeks ago
      The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 4 weeks ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community 18-year progress pics. Fin only.

      in Progress Pictures  419 upvotes 1 month ago
      The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.

      community hair loss treatment myths that perplex me

      in Treatment  8 upvotes 1 month ago
      Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

      community Well… I Did It. Estrogen Saved My Hairline

      in Transgender  714 upvotes 1 month ago
      OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

      community 2 years progress (28M). Finally posting my results

      in Update  211 upvotes 1 month ago
      A 28-year-old shared his 2-year hair loss treatment progress using finasteride, minoxidil, dermarolling, and Revita shampoo. He saw significant improvement, especially with minoxidil and dermarolling, and stressed consistency.

      community AGA evaluation and first steps - BEGINNER MEGAPOST

      in Chat  74 upvotes 1 month ago
      The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  133 upvotes 1 month ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community 20yo, dutasteride and minoxidil aren’t working

      in Finasteride/Dutasteride  117 upvotes 1 month ago
      A 20-year-old reports worsening hair loss despite using dutasteride and minoxidil, and considers a hair transplant. Users suggest continuing treatments, trying microneedling, ketoconazole shampoo, switching to finasteride, or adding tretinoin.

      community 5 months of nuking T, 2 months of minoxidil

      in Transgender  483 upvotes 2 months ago
      The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

      community Year and 3 months progress (28m) fin + min

      in Progress Pictures  328 upvotes 2 months ago
      A user shared their 15-month hair regrowth progress using 1mg finasteride daily and topical minoxidil once daily, noting significant improvement after adding finasteride. They experienced mild side effects, including reduced erection strength after a year.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 2 months ago
      The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 11 months on fin + min. Thoughts?

      in Progress Pictures  916 upvotes 2 months ago
      A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

      community Today doctor scolded me so hard💀

      in Chat  39 upvotes 2 months ago
      A 20-year-old has been using finasteride for 2 years and switched from 5% to 10% minoxidil, causing issues. The doctor now prescribes 5% minoxidil twice daily, dutasteride on alternate days, and 3 PRP sessions for hair regrowth.