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GlossarySmall Fiber Neuropathy (SFN)

condition affecting small nerve fibers causing pain and temperature issues

Small Fiber Neuropathy (SFN) is a condition that affects the small nerve fibers responsible for transmitting pain and temperature sensations. It can lead to symptoms such as burning pain, tingling, and numbness, often starting in the feet and hands. SFN can be associated with various underlying conditions, including diabetes, autoimmune diseases, and infections, and is typically diagnosed through skin biopsy or specialized nerve tests.

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community Korean 2021 study shows efficacy of sulforaphane.

in Treatment 49 upvotes 2 years ago

Sulforaphane shows potential for hair regrowth, with users reporting reduced shedding and regrowth. Some users combine it with Minoxidil and finasteride for better results.

community The theory that explains everything - First Evidence of Hair regrow attributed to upregulating 3aHSD

in Treatment 174 upvotes 3 years ago

Hair regrowth treatment involving 3aHSD enzyme shows 6% improvement in 18 weeks. Sulforaphane, L-Menthol, and Dexpanthenol are potential ingredients for new hair loss solution.

community Spanish dermatologist suggests sulforaphane for AGA

in Research/Science 13 upvotes 10 months ago

A Spanish dermatologist suggests sulforaphane for androgenetic alopecia (AGA) due to its potential to remove DHT metabolites, though high dosages are needed. A topical formulation might be possible.

community Updates on the Sulforaphane group?

in Chat 17 upvotes 3 years ago

Hair loss discussion involves experimenting with Sulforaphane from broccoli sprouts and possibly procyanidin b2. People seek updates on progress and if it's worth adding to treatment stack like microneedling.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community What happened to the ‘funding’ for broccoli research in treating hair loss?

in Chat 42 upvotes 3 years ago

Hair loss discussion includes broccoli sprouts treatment, Fluridil 7%, and sulforaphane, with mixed results. Finasteride, minoxidil, and RU58841 are preferred by some users.

community The theory that explains everything. Please help me make this big!

in Research/Science 2453 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Found it. Sulforaphane, a phytochemical in broccoli sprouts, promotes hair growth (60% regeneration in mice) by accelerating the degradation of DHT.

112 upvotes 7 years ago

Sulforaphane, found in broccoli sprouts, promotes hair growth by degrading DHT. Users discuss its potential benefits and joke about unconventional application methods.